Could Melatonin Help Women Build More Muscle and Burn More Fat?

Melatonin has been shown to support weight management and muscle gains.

Melatonin has been shown to support weight management and muscle gains.

Melatonin is a hormone secreted by the pineal gland in the brain and because it helps modulate sleep quality, it’s frequently used as a dietary supplement to lessen abnormal sleep patterns (1). However, a recent study suggests that melatonin may also assist in supporting weight management and muscle gain (2).

In the new study, researchers from Denmark evaluated melatonin’s effects on body composition, lipid and glucose metabolism, and hormones in post-menopausal women—a population with particular difficulty building and maintaining muscle (2). The researchers randomized the test subjects and supplemented them nightly with either 1 or 3 milligrams of melatonin or a placebo for 12 months (2).

(Note: The dose of melatonin used in the study is in the same range as found in Isagenix Sleep Support & Renewal™.)

In response to their year-long supplementation of melatonin, the participants’ fat mass decreased by an impressive 7 percent while lean muscle mass increased by 2.6 percent, when compared to the placebo group.

The researchers hypothesized that the improved body composition by melatonin supplementation may have been due to positive influences on body composition and energy metabolic cellular pathways (3).

Additional possibilities included enhanced bone-remodeling proteins, suppression of fat cell formation, and an indirect, stimulatory effect on growth hormone homeostasis (3).

Overall, while melatonin doesn’t directly help build muscle, it does have beneficial effects on body composition most likely due to facilitating a positive hormonal environment that supports better sleep quality and metabolism.

With age, natural melatonin production decreases resulting in reduced sleep duration and inadequate sleep quality (4). Irregular sleep patterns are associated with a wide variety of poor behaviors, such as overeating and other health problems. It’s not surprising that insufficient or poor sleep contributes to fat gain, insulin resistance, and decreased muscle mass (5).

The study highlights one of the many reasons melatonin supplementation could be a key to healthy aging. Melatonin is safe, without any of the unwanted negative side effects on blood lipids, glucose metabolism, or markers of kidney and liver health that might normally be seen with other hormonal substances that have fat-reducing and muscle-building benefits.


  1. Bubenik GA & Konturek SJ. Melatonin and aging: prospects for human treatment. J Physiol Pharmacol. 2011 Feb; 62(1):13-9.
  2. Amstrup AK, Sikjaer T, Bønløkke Pedersen S, Heickendorff L, Mosekilde L, & Rejnmark L. Reduced fat mass and increased lean mass in response to one year of melatonin treatment in postmenopausal women: A randomized placebo controlled trial. Clin Endocrinol. 2015 Sep 9. [Epub ahead of print]
  3. Valcavi R, Zini M, Maestroni GJ, Conti A & Portioli I. Melatonin stimulates growth hormone secretion through pathways other than the growth hormone-releasing hormone. Clin Endocrinol. 1993 Aug;39(2):193-9.
  4. Bubenik GA & Konturek SJ. Melatonin and aging: prospects for human treatment. J Physiol Pharmacol. 2011 Feb; 62(1):13-9.
  5. Leproult R, Holmbäck U & Van Cauter E. Circadian misalignment augments markers of insulin resistance and inflammation, independently of sleep loss. Diabetes. 2014 Jun; 63(6):1860-9.


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From Bean To Brew: The Isagenix Coffee Difference

Isagenix Coffee is a deliciously smooth way to start your day the right way. The secret behind the rich flavor of Isagenix Coffee is the unique development process that helps to ensure our freshly ground coffee produces one of the purest, best-tasting brews you’ll ever enjoy. See the no-compromise process we use to take Isagenix Coffee from bean to brew.


  • Harvested at just the right time when coffee cherries are at the peak of ripeness.
  • 100% arabica coffee from shade-grown nurseries that are selectively picked for robust levels of natural compounds and flavor.
  • Isagenix Coffee is carefully selected by a licensed coffee grader.
  • Rigorously tested for pesticides, heavy metals, and mycotoxins for maximum health and safety.
  • Our coffee is slow roasted by a certified roast master in small batches for a perfect medium roast. Our roasting process helps maximize the release of natural flavors from the bean into your morning brew.
  • Isagenix Coffee is enhanced with green tea, trace minerals, and creamy MCT oils for flavor and quality.
  • The freshly roasted coffee is carefully ground using cool grind technology. This process ensures every delicate component is captured in your cup.

How much coffee?

Have you heard the news? Most recently, the 2015 U.S. Dietary Guidelines Advisory Committee evaluated the latest scientific literature surrounding the study of coffee and determined that moderate coffee consumption can be easily incorporated into a healthy nutritional system. A moderate range is three to five cups per day, providing up to about 400 milligrams of caffeine (1). So feel free to enjoy up to five cups of Isagenix Coffee daily!

Note: This article is also found in our Fall issue of the Isagenix Research and Science newsletter. 


  1. Dietary Guidelines Advisory Committee. Scientific Report of the 2015 Dietary Guidelines Advisory Committee. Washington (DC): USDA and US Department of Health and Human Services (2015).

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How to Avoid Holiday Weight Gain

Savor your holiday celebrations without the weight gain.

Savor your holiday celebrations without the weight gain.

The holiday season is a time for fun and celebration. Unfortunately, it’s also a time for overindulgences that often lead to weight gain. As festivities draw near, it’s important to plan accordingly to have an enjoyable holiday season without packing on unwanted pounds. By remembering these three tips, you can celebrate the holidays while feeling balanced and in control.

1. Manage Post-Feast Leftovers

Overeating at just one meal is not a significant threat to your waistline, but chowing down on leftovers for a week or more can lead to excessive calories. Quickly managing leftovers in a way that removes the temptation is your best strategy.

  • If you are hosting a celebration this year, pack up leftovers and send them home with your guests. Your guests will be thankful and you won’t be left with an overstuffed refrigerator.
  • Consider freezing leftovers in individual portions. You may be less likely to have a late-night snack if you need to go to the effort of defrosting first.
  • Re-evaluate how much food you need for your family feast. If you still have leftovers in your freezer after New Year’s Day, you probably prepared too much food.

See Curb Those Holiday Cravings! Isagenix Options to Please Your Palate.

2. Enjoy Your Indulgences

Have you ever eaten something simply because it was available, but didn’t really taste it? The added stress of the holiday season combined with an abundance of calorie-laden foods represents a serious risk for mindless eating. When you choose to indulge in a treat, take the time to truly enjoy the experience. Consider how much you will enjoy that slice of leftover pumpkin pie that has been sitting on your kitchen counter. If you don’t savor it, it is not worth the calories.

3. Start Healthy Holiday Traditions

While food usually takes center stage during holiday parties, consider adding some healthy traditions into the day. Work up an appetite by participating in a physical event like an annual turkey trot or playing an active game of football in the backyard. For something a little more relaxing, take a walk outside with your family and guests before serving dessert.

Should you be concerned about gaining weight because of a one-time indulgence?

It’s commonly believed that weight gain during the holiday period is on average about five pounds or more. However, researchers studying holiday weight gain have found that the average American gains only about one pound between Thanksgiving and Christmas. Individuals who are already overweight might gain closer to two pounds on average (1).

While one to two pounds might not sound like a lot of weight, these pounds can add up over time. The seemingly small amount of weight gained over the holidays can account for much of the weight gain as we age (2). Maintaining your weight through the holidays is a powerful tool to help you stay slim. With a proper game plan in place, you can enjoy your holidays without adding extra pounds to your waistline.


  1. J.A. Yanovski, S.Z. Yanovski, K.N. Sovik, T.T. Nguyen, P.M. O’Neil, N.G. Sebring. A prospective study of holiday weight gain. N Engl J Med. 342 (23) (2000), pp. 861–867
  2. Schoeller DA. The effect of holiday weight gain on body weight. Physiol Behav. 2014 Jul;134:66-9. doi: 10.1016/j.physbeh.2014.03.018.

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Why Isagenix Coffee?


The quality of Isagenix Coffee sets it apart from the rest.

Coffee may be a common beverage, but at Isagenix we’ve sought to make coffee that stands out from its competitors with our no-compromise quality.

Isagenix Coffee is a distinctively delicious and wholesome gourmet blend of medium-roast coffee. This exceptional product is artisanal batch-produced and medium roasted under sophisticated environmental controls. It’s never over-roasted or burnt, so it retains its natural properties and distinguished flavor.

What’s the Isagenix difference between Organic and Premium?

Available in Premium and USDA-Certified Organic Blends, Isagenix Coffee is roasted using 100 percent arabica coffee beans. The USDA-Certified Organic Blend has undergone an additional certification process to ensure that the coffee beans were produced using the highest standards of organic agriculture.

What’s different about the quality of Isagenix Coffee?

The coffee beans used in Isagenix Coffee are fairly traded from around the world and are rigorously tested to ensure they have the lowest possible levels of mold and pesticides. Isagenix Coffee is infused with green tea extract to reinforce its antioxidant strength and rounded out with coconut-derived medium-chain triglycerides (MCTs) and trace minerals to offset coffee’s natural acidity for a refined, smooth, satisfying flavor.

When tested for flavor by certified Q graders, they described Isagenix Coffee this way: “The sample had a nut component in the taste with a creamy lingering finish. We were pleasantly surprised that the coffee flavor was in no way diminished with the adjuncts.”

An experienced consumer research group also found that Isagenix Coffee was preferred over other top leading brands of coffee.

Why did we choose to focus on coffee?

Coffee is a beverage consumed worldwide with more than 1.4 billion cups brewed daily, with the United States accounting for approximately 45 percent of intake (1-3).

More than half of all Americans 18 and older consume coffee on a daily basis with the average drinker consuming 3.1 cups per day (4). In the  United States, coffee sales have reached nearly US$10 billion in 2013 and the demand for coffee continues to grow with US$13 billion in sales expected by 2018 (5). Coffee is also regarded as wholesome and is generally the No. 1 source of antioxidants in the Western diet (2).

To improve the flavor of typical coffee, consumers often use calorie-laden creamers and sugar (1). There is a clear need in the marketplace for a higher-quality coffee option. The rigorous process used to create Isagenix Coffee helps ensure it is one of the purest, best-tasting brews you’ll ever enjoy. Because of its rich flavor and pleasant, smooth finish, Isagenix Coffee is delicious without any added sugar or cream.

Isagenix Coffee Features:

  • Artisanal batch medium-roasted coffee.
  • Never over-roasted to preserve chlorogenic acid and coffee’s natural properties.
  • Rigorously tested for pesticides, heavy metals, and mycotoxins.
  • Infused with green tea, coconut-derived MCTs, and trace minerals to offset acidity and round out flavor with a nutty component and satisfying finish.
  • Forget creamers — try adding Vanilla IsaPro.

Isagenix Coffee Ingredients:

  • Coffee sourced from from plants grown at high altitudes in tropical climates near the equator. The coffee beans naturally contain a variety of compounds including caffeine, chlorogenic acid, and polyphenols.
  • Green tea (Camellia sinensis) is regarded as a popular health-promoting beverage worldwide.
  • Medium-chain triglycerides (MCTs) are fatty acids found in coconut oil. The MCTs in Isagenix Coffee enhance the coffee’s smoothness and provide an improved taste and consistency compared to regular coffee, resulting in a more pleasant experience.
  • Trace minerals help offset the acidity of regular coffee while improving the nutritional profile of the beverage.

Note: This article is also found in our Fall issue of the Isagenix Research and Science newsletter. 


  1. Office of Disease Prevention and Health Promotion. Part D. Chapter 5. Food Sustainability and Safety– Continued. Scientific Report of the Dietary Guidelines Advisory Committee.
  2. Svilaas A, Sakhi AK, Andersen, LF, et al. Intakes of antioxidants in coffee, wine, and vegetables are correlated with plasma carotenoids in humans. J Nutr. 2004;134(3):562-567.
  3. International Coffee Organization.
  4. National Coffee Drinking Trends 2010, National Coffee Association.
  5. U.S. Bureau of Labor Statistics,, Information Resources Inc., Economist Intelligence Unit, Mintel.

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